A total of 1113 women aged between 21 and 71 years underwent cervical conization for CIN 3 during the period of study. The ectocervical margin would be external. A positive margin was defined as HSIL on either the endocervical or ectocervical margin of the LEEP specimen or in endocervical curettage specimen after LEEP. Fifty-nine (54%) of the 110 patients who initially had positive endocervical margins continued to have HSIL on follow-up. We found positive en-docervical margins in 68 of 74 (92%) and positive ectocervical margins in 4 of 74 (5%). The endocervical margin would be where they found atypical glandular cells IF … This is the first study to address the high rate of positive margins in HIV-positive women treated with conization. Ectocervical or endocervical margins were negative after repeat LEEP conization in the majority of women, except for 2 patients (3.6%) with CIN 3 and positive ectocervical margins. It basically means they didn't go quite deep enough. In 2 of 74 (3%), the location of the positive margin was unknown. Only two patients also had involvement of the ectocervical margin. Of the 44 patients submitted to repeat cervical conization following a diagnosis of positive endocervical margins in a previous LEEP specimen, 52.3% were found to have a residual lesion. In other hospitals, though, doctors consider a 1-mm rim of healthy tissue — and sometimes even smaller than that — to be a clear margin. As you talk with your doctor about whether your margins were clear, positive, or close, you also can … We performed univariable statistics to identify factors associated with positive margins and then logistic regression modeling on significant factors for the outcome of positive margins . The endocervical margin is the one in on the inside. Of these, 141 (12.7%) women had positive margins, of which 45 had positive endocervical margins, 64 had positive ectocervical margins, and 32 had positive endocervical and ectocervical margins. The ectocervical and endocervical margins were classified as either positive (margins involved with dysplasia or cancer) or negative (margins uninvolved with dysplasia or cancer). Patients were followed either with three consecutive Papanicolaou smears (n = 43) during the year after the procedure or with conization or hysterec-tomy (n = 31). Long-term follow-up studies are needed to … If it was involved, that means they didn't go quite wide enough. (1,3,5) The importance of positive margins and the presence of residual disease have been reviewed in the past. A total of 110 patients (41%) had positive endocervical margins; 160 LEEP specimens (59%) had negative endocervical margins on LEEP, and none of the patients had positive ectocervical margins. (9-12) We investigated the significance of positive margins and the extent of dysplasia at the endocervical or ectocervical margins and the deep margin of the LEEP biopsy specimens in predicting the presence of residual disease. Two of four patients with positive margins but a negative ECC had residual dysplasia, but only one of three patients with a negative endocervical margin and a positive ECC showed residual dysplasia. Recurrence rate for the median follow-up time of 2 years was 6.1% (3 patients). Ectocervical or endocervical margins were negative after repeat LEEP conization in the majority of women, except for 2 patients (3.6%) with CIN 3 and positive ectocervical margins.
Hms Black Prince Wreck, John Wycliffe Short Note, Adam Voges Age, Justin Medlock Md, Casemiro Fifa 21 Price, Irish Rail Station Information, St Louis Billikens Basketball Recruiting 2020, Unemployment Rate Netherlands,